18 mm Parallel Twin-Screw Extruder and Glove Box

Three-Tec offers a High Containment system with integrated gravimetric dosing unit, extruder, conveyor belt and granulator in accordance with ISO 14644-7. As a result, the process – from powder mixing to finished granulate – takes place in a protected and controlled environment, which removes the need to set up a complete clean room. The integrated machinery is designed especially for handling with gloves and can be dismantled and cleaned easily by a user. The drives of the integrated production line are either located outside the High Containment or encased. The working chambers and all the components coming into contact with the product within the machinery integrated into the High Containment are made from stainless steel 1.4404 (316 L) with a surface finish of Ra ≤ 0.8µ. Through the controlled and filtered supply and exhaust air, a controlled low pressure is created in compliance with purity class C (OEB 4 / 5) in accordance with GMP guidelines and guarantees no product escaping (inflow) even if a glove tears. In addition, the failsafe components, automatic pressure holding test and static EPDM front pane seal ensure the safety of the user and the environment. All filters and gloves can be replaced without contamination. The filling of the gravimetric feed unit in the High Containment and the removal of the finished granulate occur via the interlock sluices, twin-door sluices or twin-valve sluices (RTP port).The whole system can also be equipped with gas / compressed air extraction points, cleaning guns / WIP nozzles, vacuum cleaning system and initiation and is also built as an explosion-protected and anti-static design.